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Casting announced for Lucy Prebble's The Effect at the Boulevard Theatre

The Effect

Casting news

CASTING has been announced for the first London revival of The Effect. Written by award-winning writer Lucy Prebble and directed by Anthony Neilson, it runs at the Boulevard Theatre from March 19 to May 30, 2020.

The line up includes Eric Kofi Abrefa as Tristan Frey, Christine Entwisle as Lorna James, Tim McMullan as Toby Sealey and Kate O’Flynn as Connie Hall.

Winner of the Critics’ Circle Award for Best New Play when it opened at the National Theatre in 2012, The Effect places modern medicine under the microscope, examining the fallout from a collision between love and science.

Connie and Tristan meet; symptoms develop. Racing hearts. Lost appetites. Erratic emotions. Is this the frenzy of falling in love, or simply side effects from the new anti-depressant drug they’re testing? Addiction comes hard and fast. But have the clinicians running the trial lost control?

Eric Kofi Abrefa most recently starred in the film Blue Story, directed by Rapman. His other films include Jurassic World and Fury alongside Brad Pitt. On stage, he played Jean opposite Vanessa Kirby in Julie at the National Theatre where his credits also include A Taste of Honey alongside Kate O’Flynn. Other theatre credits include ear for eye (Royal Court) and One Love: Bob Marley Musical (Birmingham REP).

Abrefa has also featured in a number of television shows including a leading role in Channel 4’s Humans and appearances in Amazon’s Jack Ryan and Hulu’s Harlots.

Christine Entwisle’s recent theatre credits include The Monstrous Heart (Stephen Joseph Theatre), The Twits, Hope and Primetime (all Royal Court), as well as a number of plays at the RSC, including Romeo and Juliet. Her TV credits include Vera, Doctors and Holby City.

Tim McMullan has appeared in a number of shows at the National Theatre including Antony & Cleopatra, Common, Twelfth Night, Man vs Superman and The Cherry Orchard. His other theatre credits include King Charles III (West End), while TV and film credits include Netflix’s The Crown, Shakespeare in Love and The Fifth Element.

Kate O’Flynn is currently appearing in all of it at the Royal Court, where her credits also include Blank, The End of History and Anatomy of a Suicide. At the National Theatre, she has performed in Port, for which she won the Critics’ Circle Award for Most Promising Newcomer, and A Taste of Honey. Her TV and film highlights include Mike Leigh’s Happy Go Lucky and Mr. Turner, BBC’s Wanderlust, and Channel 4’s Brexit.

The Effect is designed by Natasha Jenkins, with lighting design by Nigel Edwards, sound design by Helen Skiera and casting by Julia Horan CDG.

For more information or to buy tickets, visit

Read more about the Boulevard Theatre’s 2020 Season.